Page 24 - NAMAH-Apr-2018
P. 24

Namah                                    Vol. 26, Issue 1, 24th April 2018






         Multiple                    Both 4g. and 8g. daily     A double-blind placebo-
         myeloma                     doses reduced the serum    controlled cross-over
                                     free light chain ratio (35%   of 19 patients with
                                     and 36%, respectively)     MGUS and 17 patients
                                     and reduced total serum    with smouldering MM
                                     protein (P=0.04) in the urine  examined the effects of
                                     in both MGUS and SMM       daily curcumin.
                                     patients Curcumin also
                                     decreased markers of bone
                                     turnover (urinary DPYD)
                                     and excretion of crosslinked
                                     N-telopeptides by more
                                     than 25% (23).
         Pancreatic      12 months   There was improvement      8 g. curcumin with
         cancer                      of chemotherapy-related    gemcitabine (Gemzar).
                                     symptoms after starting
                                     curcumin. The median
                                     survival after initiation of
                                     curcumin was 161 days.
                                     One-year survival rate was
                                     19%. Median survival after
                                     gemcitabine is 70 days (24).
         Prostate        6 months    Isoflavones and curcumin   100 mg. of curcumin and
         cancer                      could modulate serum       40 mg of isoflavones;
                                     PSA levels. The authors    and placebo.
                                     of this study concluded
                                     that curcumin presumably
                                     synergizes with isoflavones
                                     to suppress PSA production
                                     (25).


        Other inflammatory diseases: select clinical findings
                         Other inflammatory diseases: select clinical data
            Disease    Duration,         Benefit                    Dosage
                         below
         Arthritis     8 months   Improved joint pain,   Curcuminoid and
                                  stiffness, physical    phosphotidylcholine 1000 mg.
                                  function, social and   curcuma extract 200 curcuma
                                  emotional function (26).  extract daily.
                                                         Standard conventional treatment.



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