Page 30 - NAMAH-Jan-2018
P. 30

Namah                                  Vol. 26, Issue 4, 15th January 2019





                                                                    extracts of OS in
                                                                    a fixed oral dose
                                                                    regime 500 mg. 2t/d
         Diabetes type II     Human trial  •  The Ocimum          • All diabetics, total
                              30 days        sanctum (OS)           sample size = 27
                                             group exhibited        (male = 17 & female
                                             a reduction in         = 10) type II diabetes
                                             the fasting blood
                                             glucose levels, while   • All patients to take 1
                                             the total control      g. of OS powder, first
                                             group had higher       thing in the morning
                                             levels of glucose
                                             (13).
         Immunomodulatory     Human trial  •  The Ocimum sanctum  •  Double-blind,
                              4 weeks        (OS) leaves group      randomised control
                                             in contrast to the     trial on 24 healthy
                                             placebo group were     volunteers
                                             supportive of a      •  Daily intake of
                                             healthy immune         300 mg. ethanolic
                                             system (14).           extract of OS
                                                                    leaves on an empty
                                                                    stomach or placebo
         Stress               Human trial  •  The study           •  Extract of OT. An
                              6 weeks        demonstrated that      adult study, sample
                                             lower levels of stress   sizes:
                                             were observed in        Placebo = 79
                                             control group taking     OT extract = 71;
                                             Ocimum tenuiflorum     were given 1,200
                                             (OT). The extract      mg of extract daily
                                             was well tolerated     for six weeks
                                             for the six weeks
                                             (15).
         Gastric ulcer        Rat study 5   •  Optimal effective   •  The standardised
                              days           dose 100 mg/kg of      methanolic extract
                                             Ocimum sanctum         of leaves of OS
                                             (OS) extract showed    eugenol content 5%
                                             significant ulcer      given in doses of 50-
                                             protection and         200 mg/kg, orally,
                                             significantly healed   twice daily for five
                                             ulcers (16)            days.



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